Mouse Hikeshi activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hikeshi
Locus ID	67669
Kit Components	GA207447G1, Hikeshi gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207447G2, Hikeshi gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207447G3, Hikeshi gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291286, NM_001291287, NM_001291288, NM_001291289, NM_026304, NR_111916, NR_153788
Synonyms	0610007P06Rik; 1110002N09Rik; l(7)6Rn; l7Rn6
Summary	Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity). May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.[UniProtKB/Swiss-Prot Function]

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