Mouse Rgs8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs8
Locus ID	67792
Kit Components	GA207521G1, Rgs8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207521G2, Rgs8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207521G3, Rgs8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347115, NM_026380, NM_001357525
Synonyms	6530413N01Rik
Summary	Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling.[UniProtKB/Swiss-Prot Function]

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