Mouse Slc25a11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc25a11
Locus ID	67863
Kit Components	GA207552G1, Slc25a11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207552G2, Slc25a11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207552G3, Slc25a11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024211
Synonyms	2oxoc; 2310022P18Rik
Summary	Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity). Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (By similarity). Involved in the regulation of apoptosis (PubMed:21448454).[UniProtKB/Swiss-Prot Function]

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