Mouse Dennd10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dennd10
Locus ID	67894
Kit Components	GA207574G1, Dennd10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207574G2, Dennd10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207574G3, Dennd10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167829, NM_001347464, NM_026437, NM_001360619, NM_001360620
Synonyms	1810055E12Rik
Summary	Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.[UniProtKB/Swiss-Prot Function]

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