Mouse Poglut3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Poglut3
Locus ID	68304
Kit Components	GA207772G1, Poglut3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207772G2, Poglut3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207772G3, Poglut3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_212445
Synonyms	2010004J24Rik; 4833410J10Rik; AW549401
Summary	Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.[UniProtKB/Swiss-Prot Function]

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