Mouse Steap3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Steap3
Locus ID	68428
Kit Components	GA207809G1, Steap3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207809G2, Steap3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207809G3, Steap3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001085409, NM_133186
Synonyms	1010001D01Rik; pHyde; Tsap6
Summary	Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Also mediates reduction of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.[UniProtKB/Swiss-Prot Function]

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