Mouse Gpihbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gpihbp1
Locus ID	68453
Kit Components	GA207817G1, Gpihbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207817G2, Gpihbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207817G3, Gpihbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347039, NM_026730, NM_001361294
Synonyms	1110002J19Rik; GPI-HBP1
Summary	Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (PubMed:20620994). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (PubMed:20620994, PubMed:24726386, PubMed:27811232). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:17403372). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:18340083). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (PubMed:12496272).[UniProtKB/Swiss-Prot Function]

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