Mouse Trim37 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trim37
Locus ID	68729
Kit Components	GA207909G1, Trim37 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207909G2, Trim37 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207909G3, Trim37 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_197987
Synonyms	1110032A10Rik; 2810004E07Rik; AI848587; AU043018; mKIAA0898; MUL; TEF3
Summary	The protein encoded by this gene is part of the tripartite-motif containing family (TRIM), which is typified by the RING, B-box type 1, B-box type 2, and coiled-coil region domains. In mouse this protein is proposed to oligomerize through its coiled coil domain and has been reported to be expressed in neural crest-derived tissues as well as in tissues whose development is regulated by mesenchymal-epithelial interactions. In humans, mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder characterized by prenatal onset growth failure, cardiomyopathy and dysmorphic features. [provided by RefSeq, Jan 2013]

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