Mouse Ppp4r3a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ppp4r3a
Locus ID	68734
Kit Components	GA207911G1, Ppp4r3a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207911G2, Ppp4r3a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207911G3, Ppp4r3a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160214, NM_211355
Synonyms	1110034C04Rik; BC064465; mKIAA2010; Smek1
Summary	Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair (By similarity).[UniProtKB/Swiss-Prot Function]

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