Mouse Dock5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dock5
Locus ID	68813
Kit Components	GA207946G1, Dock5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207946G2, Dock5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207946G3, Dock5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177780
Synonyms	1110060D06Rik; AI666732; AI956923; BC016533; E130320D18; lr2; rlc
Summary	Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (PubMed:18396277). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (By similarity).[UniProtKB/Swiss-Prot Function]

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