Mouse Disp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Disp1
Locus ID	68897
Kit Components	GA207971G1, Disp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207971G2, Disp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207971G3, Disp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278218, NM_001278219, NM_001278220, NM_026866
Synonyms	1190008H24Rik; DispA
Summary	Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion (PubMed:22902404).[UniProtKB/Swiss-Prot Function]

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