Mouse Tmco1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmco1
Locus ID	68944
Kit Components	GA207986G1, Tmco1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207986G2, Tmco1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207986G3, Tmco1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039483, NM_026881
Synonyms	1190006A08Rik; 4930403O06Rik; AA109065; AU022572; ESTM39
Summary	Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis (PubMed:27212239). In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (PubMed:27212239).[UniProtKB/Swiss-Prot Function]

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