Mouse Cdk13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdk13
Locus ID	69562
Kit Components	GA208227G1, Cdk13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208227G2, Cdk13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208227G3, Cdk13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081058, NM_027118
Synonyms	2310015O17Rik; Cdc2l5
Summary	Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis.[UniProtKB/Swiss-Prot Function]

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