Mouse Acot7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Acot7
Locus ID	70025
Kit Components	GA208399G1, Acot7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208399G2, Acot7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208399G3, Acot7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146057, NM_001146058, NM_133348, NM_001369273, NM_001369274, NM_001369275, NM_001369276
Synonyms	2410041A17Rik; Ach1; Act; Bach; Cte-II; CTE-IIa; Lach1
Summary	Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:15288813). Acyl-coenzyme A thioesterase 7/ACOT7 preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18 (Probable). May play an important physiological function in brain (PubMed:15288813).[UniProtKB/Swiss-Prot Function]

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