Mouse Iyd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Iyd
Locus ID	70337
Kit Components	GA208480G1, Iyd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208480G2, Iyd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208480G3, Iyd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027391
Synonyms	0610009A07Rik; AI265638; Dehal1
Summary	Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT) (PubMed:22238141). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine (By similarity).[UniProtKB/Swiss-Prot Function]

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