Mouse Tecpr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tecpr1
Locus ID	70381
Kit Components	GA208499G1, Tecpr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208499G2, Tecpr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208499G3, Tecpr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027410, NM_001356992, NM_001356993
Synonyms	2210010N04Rik; mKIAA1358
Summary	Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).[UniProtKB/Swiss-Prot Function]

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