Mouse Tspan15 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tspan15
Locus ID	70423
Kit Components	GA208515G1, Tspan15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208515G2, Tspan15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208515G3, Tspan15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_197996
Synonyms	1110036D12Rik; 2700063A19Rik; AW048364; Tm4sf15
Summary	Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:23035126, PubMed:26668317). Promotes ADAM10-mediated cleavage of (CDH2) (PubMed:26668317). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (By similarity).[UniProtKB/Swiss-Prot Function]

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