Mouse Atp6ap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atp6ap2
Locus ID	70495
Kit Components	GA208541G1, Atp6ap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208541G2, Atp6ap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208541G3, Atp6ap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027439
Synonyms	(P)RR; 5730403E06Rik; APT6M8-9; Atp6ip2; ATP6M8-9; M8-9; PRR
Summary	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).[UniProtKB/Swiss-Prot Function]

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