Mouse Zcchc8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zcchc8
Locus ID	70650
Kit Components	GA208590G1, Zcchc8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208590G2, Zcchc8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208590G3, Zcchc8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027494
Synonyms	5730565F05Rik
Summary	Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. May be involved in pre-mRNA splicing.[UniProtKB/Swiss-Prot Function]

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