Mouse Tdrd12 activation kit by CRISPRa
CAT#: GA209043
Tdrd12 CRISPRa kit - CRISPR gene activation of mouse tudor domain containing 12
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Tdrd12 |
Locus ID | 71981 |
Kit Components | GA209043G1, Tdrd12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209043G2, Tdrd12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209043G3, Tdrd12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001082581, NM_028034, NM_001368387 |
Synonyms | 2410004F06Rik; 2410070K17Rik; ECAT8; EG434165; G1-476-14; repro23 |
Summary | Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:24067652). Involved in the secondary piRNAs metabolic process (PubMed:24067652). Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs (PubMed:26669262).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN517375 | Tdrd12 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |