Mouse Tmem175 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem175
Locus ID	72392
Kit Components	GA209224G1, Tmem175 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209224G2, Tmem175 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209224G3, Tmem175 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163531, NM_001163532, NM_028223, NM_001359423, NM_001359426, NM_001359427
Synonyms	3010001K23Rik; AI504381; mTMEM175
Summary	Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.[UniProtKB/Swiss-Prot Function]

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