Mouse Adipor1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adipor1
Locus ID	72674
Kit Components	GA209311G1, Adipor1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209311G2, Adipor1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209311G3, Adipor1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028320
Synonyms	2810031L11Rik; ACDCR1; CGI-45; Paqr1
Summary	This gene encodes a receptor for the fat-derived hormone adiponectin. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. Homozygous knockout mice for this gene exhibit elevated plasma glucose and insulin levels as well as impaired glucose tolerance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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