Mouse Dhx30 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dhx30
Locus ID	72831
Kit Components	GA209351G1, Dhx30 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209351G2, Dhx30 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209351G3, Dhx30 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252682, NM_001252683, NM_133347
Synonyms	2810477H02Rik; C130058C04Rik; Ddx30; HELG; Ret-CoR
Summary	RNA-dependent helicase (PubMed:25219788). Plays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA (By similarity). Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (PubMed:25219788).[UniProtKB/Swiss-Prot Function]

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