Mouse Sgip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sgip1
Locus ID	73094
Kit Components	GA209399G1, Sgip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209399G2, Sgip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209399G3, Sgip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001285852, NM_001285859, NM_001285860, NM_001285862, NM_144906
Synonyms	3110007P09Rik; gag; SGIP1alpha
Summary	May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.[UniProtKB/Swiss-Prot Function]

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