Mouse Kif2c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kif2c
Locus ID	73804
Kit Components	GA209609G1, Kif2c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209609G2, Kif2c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209609G3, Kif2c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290662, NM_134471
Synonyms	4930402F02Rik; ESTM5; Knsl6; MCAK; X83316
Summary	In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:14980225). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (By similarity).[UniProtKB/Swiss-Prot Function]

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