Mouse Sec14l1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sec14l1
Locus ID	74136
Kit Components	GA209737G1, Sec14l1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209737G2, Sec14l1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209737G3, Sec14l1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166506, NM_001166507, NM_028777, NR_029459, NM_001363165
Synonyms	1200017E04Rik; 2810012L19Rik; Naa-35
Summary	May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.[UniProtKB/Swiss-Prot Function]

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