Mouse Josd1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Josd1
Locus ID	74158
Kit Components	GA209752G1, Josd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209752G2, Josd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209752G3, Josd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028792
Synonyms	1300006C06Rik; mKIAA0063
Summary	Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity (By similarity).[UniProtKB/Swiss-Prot Function]

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