Mouse Elp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Elp3
Locus ID	74195
Kit Components	GA209775G1, Elp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209775G2, Elp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209775G3, Elp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001253812, NM_028811, NR_045599
Synonyms	2610507P14Rik; KAT9
Summary	Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin (By similarity). May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (PubMed:19185337).[UniProtKB/Swiss-Prot Function]

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