Mouse Tktl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tktl2
Locus ID	74419
Kit Components	GA209876G1, Tktl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209876G2, Tktl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209876G3, Tktl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271574, NM_028927
Synonyms	4933401I19Rik
Summary	Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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