Mouse Syce3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Syce3
Locus ID	75459
Kit Components	GA210222G1, Syce3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210222G2, Syce3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210222G3, Syce3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001162880, NM_001162882
Synonyms	1700007E06Rik; TSEG-2; TSEG2
Summary	Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. May play a role in apoptosis of spermatogenic cells and pathogenesis of cryptorchidism.[UniProtKB/Swiss-Prot Function]

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