Mouse Ripor1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ripor1
Locus ID	75687
Kit Components	GA210310G1, Ripor1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210310G2, Ripor1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210310G3, Ripor1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081241
Synonyms	2310066E14Rik; AI837433
Summary	Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.[UniProtKB/Swiss-Prot Function]

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