Mouse Gpsm2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gpsm2
Locus ID	76123
Kit Components	GA210436G1, Gpsm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210436G2, Gpsm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210436G3, Gpsm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029522
Synonyms	6230410J09Rik; LGN; Pins
Summary	Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase (By similarity). Plays a role in metaphase spindle orientation (By similarity). Plays an important role in asymmetric cell divisions (PubMed:12571286, PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (PubMed:22952234).[UniProtKB/Swiss-Prot Function]

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