Mouse Med13l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Med13l
Locus ID	76199
Kit Components	GA210454G1, Med13l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210454G2, Med13l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210454G3, Med13l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347445, NM_172424
Synonyms	2210413I17Rik; 6330591G05Rik; 9030618F05Rik; mKIAA1025; Thrap2; Trap240L
Summary	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]

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