Mouse 1700028K03Rik activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	1700028K03Rik
Locus ID	76421
Kit Components	GA210506G1, 1700028K03Rik gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210506G2, 1700028K03Rik gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210506G3, 1700028K03Rik gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175241, NM_182745
Synonyms	MGC117884
Summary	Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (PubMed:30949703). Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (PubMed:30746471). Required for the localization of TEX11 and MSH4 to recombination intermediates (PubMed:30746471).[UniProtKB/Swiss-Prot Function]

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