Mouse Gid8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gid8
Locus ID	76425
Kit Components	GA210507G1, Gid8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210507G2, Gid8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210507G3, Gid8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289651, NM_001289652, NM_029607
Synonyms	2310003C23Rik; 4833420G11Rik; AI451474; Twa1
Summary	Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.[UniProtKB/Swiss-Prot Function]

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