Mouse Fbxo31 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo31
Locus ID	76454
Kit Components	GA210513G1, Fbxo31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210513G2, Fbxo31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210513G3, Fbxo31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133765
Synonyms	1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14
Summary	Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest (By similarity).[UniProtKB/Swiss-Prot Function]

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