Mouse Dok5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dok5
Locus ID	76829
Kit Components	GA210629G1, Dok5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210629G2, Dok5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210629G3, Dok5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163686, NM_029761
Synonyms	2700055C10Rik
Summary	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.[UniProtKB/Swiss-Prot Function]

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