Mouse B3gat1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	B3gat1
Locus ID	76898
Kit Components	GA210649G1, B3gat1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210649G2, B3gat1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210649G3, B3gat1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310766, NM_029792
Synonyms	0710007K08Rik; AI846286; GlcAT-P; Glcatp; Hnk1
Summary	Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.[UniProtKB/Swiss-Prot Function]

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