Mouse Ticrr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ticrr
Locus ID	77011
Kit Components	GA210683G1, Ticrr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210683G2, Ticrr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210683G3, Ticrr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029835
Synonyms	5730590G19Rik; BC028450; Lrrk1
Summary	Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation (By similarity).[UniProtKB/Swiss-Prot Function]

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