Mouse Mrap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mrap
Locus ID	77037
Kit Components	GA210691G1, Mrap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210691G2, Mrap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210691G3, Mrap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029844
Synonyms	1110025G12Rik; C21ORF61; Falp; ORF61
Summary	Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells (By similarity).[UniProtKB/Swiss-Prot Function]

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