Mouse Klhl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Klhl2
Locus ID	77113
Kit Components	GA210710G1, Klhl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210710G2, Klhl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210710G3, Klhl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178633
Synonyms	6030411N21Rik; ABP-KELCH; AU020744; Mav
Summary	Promotes growth of cell projections in oligodendrocyte precursors. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 (By similarity). Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Plays a role in the reorganization of the actin cytoskeleton.[UniProtKB/Swiss-Prot Function]

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