Mouse Wdr82 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wdr82
Locus ID	77305
Kit Components	GA210736G1, Wdr82 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210736G2, Wdr82 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210736G3, Wdr82 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029896
Synonyms	9430077D24Rik; CDW5/WDR82
Summary	Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Possible role in telomere length maintenance and in mRNA processing (By similarity).[UniProtKB/Swiss-Prot Function]

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