Mouse Limch1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Limch1
Locus ID	77569
Kit Components	GA210769G1, Limch1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210769G2, Limch1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210769G3, Limch1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001980, NM_001256122, NM_001368863
Synonyms	3732412D22Rik; mKIAA1102
Summary	Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration.[UniProtKB/Swiss-Prot Function]

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