Mouse Ascc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ascc3
Locus ID	77987
Kit Components	GA210857G1, Ascc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210857G2, Ascc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210857G3, Ascc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146089, NM_198007
Synonyms	ASC1p200; B630009I04Rik; BC023451; D430001L07Rik; D630041L21; Helic1; RNAH
Summary	3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation.[UniProtKB/Swiss-Prot Function]

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