Mouse Mvp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mvp
Locus ID	78388
Kit Components	GA210953G1, Mvp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210953G2, Mvp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210953G3, Mvp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_080638
Synonyms	2310009M24Rik; LRP; VAULT1
Summary	Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).[UniProtKB/Swiss-Prot Function]

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