Mouse Osbpl5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osbpl5
Locus ID	79196
Kit Components	GA211085G1, Osbpl5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211085G2, Osbpl5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211085G3, Osbpl5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199227, NM_024289
Synonyms	1110006M06Rik; AI462538; Obph1; ORP5; Osbp2
Summary	Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol.[UniProtKB/Swiss-Prot Function]

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