Mouse Apobec3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apobec3
Locus ID	80287
Kit Components	GA211109G1, Apobec3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211109G2, Apobec3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211109G3, Apobec3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160415, NM_001347041, NM_030255
Synonyms	Apobec; Arp3; BC003314; Cem15; Rfv3
Summary	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against HIV-1, simian immunodeficiency viruses (SIVs), mouse mammary tumor virus (MMTV) and friend murine leukemia virus (FrMLV) and may inhibit the mobility of LTR retrotransposons.[UniProtKB/Swiss-Prot Function]

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