Mouse Pacsin3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pacsin3
Locus ID	80708
Kit Components	GA211122G1, Pacsin3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211122G2, Pacsin3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211122G3, Pacsin3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289677, NM_001289678, NM_028733, NM_030880
Synonyms	4921507A02Rik; 6330413E15Rik; AW413130
Summary	Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.[UniProtKB/Swiss-Prot Function]

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