Mouse Ndst3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ndst3
Locus ID	83398
Kit Components	GA211212G1, Ndst3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211212G2, Ndst3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211212G3, Ndst3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293682, NM_031186, NR_121616
Synonyms	4921531K01Rik; 4930511P15Rik; N-HSST 3; NDST-3
Summary	Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity.[UniProtKB/Swiss-Prot Function]

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