Mouse Wwtr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wwtr1
Locus ID	97064
Kit Components	GA211463G1, Wwtr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211463G2, Wwtr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211463G3, Wwtr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168281, NM_133784
Synonyms	2310058J06Rik; 2610021I22Rik; C78399; Taz
Summary	This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

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